18F-FDG PET/CT can detect left ventricular wall inflammation in eosinophilic myocarditis, showing findings consistent with MRI gadolinium enhancement.
18F-FDG PET/CT may aid detection of eosinophilic myocarditis; leaves open routine use pending prospective data.
Late-stage eosinophilic myocarditis (or Löffler endocarditis) is known to occur in patients with hypereosinophilic syndrome and can cause restrictive cardiomyopathy. Eosinophilic myocarditis is an acute life-threatening inflammatory disease of the heart that can be associated with cancer. We report a case of a 70-year-old White woman, previously treated for diffuse large B-cell lymphoma in remission, admitted for acute dyspnea with a 1-year history of hypereosinophilia. 18F-FDG PET/CT revealed endocardial uptake consistent with MRI gadolinium enhancement, suggesting left ventricular wall inflammation.
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Peslier et al. (2024) studied this question.
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