Why the study?
Does Ethylisopropylamiloride (EIPA) block the sodium current in cultured embryonic chick atrial myocytes?
Does Ethylisopropylamiloride (EIPA) block the sodium current in cultured embryonic chick atrial myocytes?
EIPA acts as an open-channel blocker of the cardiac sodium current at concentrations comparable to those of many type I antiarrhythmic agents.
No takes yet. Share an insight, caveat, or question.
EIPA may serve as experimental INa blocker in avian models; leaves open translation to mammalian antiarrhythmic effects.
Gold et al. (1991) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: