Why the study?
Data regarding PRRSV-1 vaccine virus strain dissemination within vaccinated sow herds and transmission to offspring are scarce, impacting PRRSV diagnostic strategies and recombination risks.
Does sow mass vaccination with a PRRSV-1 modified live virus vaccine lead to vaccine virus dissemination in due-to-wean piglets?
Does sow mass vaccination with a PRRSV-1 modified live virus vaccine lead to vaccine virus dissemination in due-to-wean piglets?
Dissemination of the PRRSV-1 modified live vaccine strain from vaccinated sows to due-to-wean piglets appears to be a rare event.
Scarce PRRSV-1 MLV data in sows; leaves open optimal diagnostics and vaccination to limit offspring transmission risks.
Data concerning PRRSV-1 vaccine virus strains dissemination within vaccinated sow herds are scarce. However, it is a big concern for swine practitioners when designing the PRRSV diagnostics strategy in vaccinated farms. At the same time, the possibility of vaccine virus transmission from sows to their offspring is important to have in mind in order to limit the risk of recombination between different PPRSV-1 modified live virus vaccine (MLV1) when both sows and piglets have to be vaccinated. This study was conducted in five PRRSV-stable breeding herds. The selected farms presented different characteristics regarding production parameters and biosecurity management practices in order to be, as much as possible, representative of French swine production herds. In four different batches following a sow mass vaccination with a PRRSV-1 modified live virus vaccine (ReproCyc® PRRS EU, Boehringer Ingelheim, Ingelheim, Germany), we failed to detect the vaccine virus in due-to-wean piglets in all of the herds. This should mean that the dissemination of the vaccinal strain is a rare event, even just after a sow vaccination, at least for the vaccine tested in our study.
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Lebret et al. (2023) studied this question.
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