Summary. The distribution and excretion of Sr 90 and Ca 45 was studied at varying intervals after simultaneous intraperitoneal injection of the isotopes to young rats. Sr 90 was retained to a lesser extent than Ca 45 owing to the preferential excretion (or failure of reabsorption) of the former element by the kidneys as well as by the gastrointestinal tract. With regard to skeletal accretion and exchange there was no marked difference between the two elements. The importance of the accretion process for the fixation of the isotopes in the skeleton is emphasized. The computation of the rate of Ca accretion in the whole skeleton is described.
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Bauer et al. (1955) studied this question.
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