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IgG4-related disease (IgG4-RD) is a rare, multisystem, fibroinflammatory disorder with characteristic histopathology. Ongoing research continues to define optimal disease evaluation and management. We report our experience with IgG4 sialadenitis and the effectiveness of serial salivary gland ultrasound to monitor this insidious disease course and response to treatment. Specifically, we note the improvement in abnormal gland echotexture and inflammation in response to rituximab therapy. Such findings may have future applications for international classification criteria and/or treatment response.
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Trang et al. (2025) studied this question.
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