March 15, 1973Philosophical transactions of the Royal Society of London. Series B, Biological sciences

Smooth muscle: contraction hypothesis based on the arrangement of actin and myosin filaments in different states of contraction*

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Population

Mouse taenia coli (smooth muscle)

Design

Preclinical

Authors

HHH. HeumannUniversity of Tübingen

Discussion

Member takes

Implication

Early ultrastructural data support sliding filament model in animal smooth muscle; leaves open confirmation in human cardiovascular tissues.

Structured PICO

Population

Mouse taenia coli (smooth muscle)

Intervention

Observation of different states of contraction (relaxed vs shortened)

Outcome

Arrangement of actin and myosin filamentssurrogate

Proposes a sliding filament model for smooth muscle contraction based on electron microscopy of mouse taenia coli showing intermingling of thick and thin filaments during contraction.

Cite This Study

H. Heumann (1973) studied this question.

synapsesocial.com/papers/6a756e0d01b447f0dadc22b3 https://doi.org/10.1098/rstb.1973.0025

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Implication

Early ultrastructural data support sliding filament model in animal smooth muscle; leaves open confirmation in human cardiovascular tissues.

Smooth muscle: contraction hypothesis based on the arrangement of actin and myosin filaments in different states of contraction*

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Smooth muscle: contraction hypothesis based on the arrangement of actin and myosin filaments in different states of contraction*

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider