Why the study?
Does mild paravalvular regurgitation post TAVI increase mortality compared to none/trivial PVR?
Population
21,018 patients who underwent transcatheter aortic valve implantation (TAVI) pooled from 25 articles
Comparison
Mild paravalvular regurgitation (PVR) post TAVI vs None/trivial PVR post TAVI
Design
Meta-analysis
Follow-up
6 months to 5 years
Authors
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Mild PVR after TAVI was associated with higher mortality; confirms the link in pooled data but leaves open whether intervention improves outcomes.
Does mild paravalvular regurgitation post TAVI increase mortality compared to none/trivial PVR?
Mild paravalvular regurgitation after TAVI is associated with increased all-cause and cardiovascular mortality, suggesting it is not a benign finding.
Ando et al. (2017) studied this question.
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