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March 29, 2022CureusOpen Access

Myocardial Infarction With Non-obstructive Coronary Arteries: An Updated Overview of Pathophysiology, Diagnosis, and Management

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Why the study?

Therapeutic management of MINOCA is limited by a lack of evidence-based literature and prospective randomized controlled studies, and patient prognosis remains unclear.

Design

Review

Authors

AKArshan KhanUniversity of Central FloridaALAbdelilah LahmarMohammed V UniversityMRMaria RiasatMount Sinai Health System

Discussion

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Implication

Etiology-specific evaluation is warranted in young women with MINOCA; leaves open prospective trials to refine management.

Structured PICO

P
Population
Patients with Myocardial Infarction With Non-obstructive Coronary Arteries (MINOCA)

MINOCA should be considered a working diagnosis requiring further investigation with advanced imaging to determine the underlying etiology and guide patient-specific management.

Cite This Study

Khan et al. (2022) studied this question.

synapsesocial.com/papers/6a7570671078cf7de2b21bbchttps://doi.org/10.7759/cureus.23602
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Mechanisms of Myocardial Infarction in Women Without Angiographically Obstructive Coronary Artery Disease2011 · 477 citations
  2. 2Spontaneous Coronary Artery Dissection: A Rare Manifestation of Alport Syndrome2017 · 14 citations
  3. 3Clinical characteristics and outcome in patients with ST-segment and non-ST-segment elevation myocardial infarction without obstructive coronary artery: an observation study from Chinese population2022 · 11 citations
  4. 4Medical Therapy for Secondary Prevention and Long-Term Outcome in Patients With Myocardial Infarction With Nonobstructive Coronary Artery Disease2017 · 487 citations
  5. 5Patients with acute myocardial infarction and non-obstructive coronary arteries: safety and prognostic relevance of invasive coronary provocative tests2017 · 326 citations