Why the study?
Does SSRI/SNRI use increase the risk of perioperative bleeding or transfusion in adult patients undergoing cardiac surgery with cardiopulmonary bypass?
Population
2,834 adult patients (1,417 propensity-matched pairs) undergoing cardiac surgery with cardiopulmonary bypass
Comparison
Selective serotonin reuptake inhibitors or… vs Propensity-matched control patients not taking…
Design
Cohort
Follow-up
30 days
Authors
Loading...
May support continuing SSRI/SNRI perioperatively in cardiac surgery; leaves open need for prospective confirmation.
Does SSRI/SNRI use increase the risk of perioperative bleeding or transfusion in adult patients undergoing cardiac surgery with cardiopulmonary bypass?
SSRI/SNRI use is not associated with an increased risk of bleeding or transfusion in cardiac surgery patients, suggesting that routine perioperative interruption of these medications is unwarranted.
Smith et al. (2017) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: