Why the study?
Does empiric superior vena cava isolation improve freedom from atrial fibrillation compared to a conventional approach in patients undergoing AF ablation?
Does empiric superior vena cava isolation improve freedom from atrial fibrillation compared to a conventional approach in patients undergoing AF ablation?
Empiric superior vena cava isolation during AF ablation provides similar AF freedom rates to a conventional targeted approach but carries risks of specific complications, making its routine use controversial.
Empiric SVCI yields similar AF freedom to conventional ablation; leaves open whether selective use reduces complications without compromising efficacy.
Superior vena cava (SVC) is one of the most important non-pulmonary vein (PV) origins of atrial fibrillation (AF). SVC isolation (SVCI) is effective especially in patients with paroxysmal AF from SVC origin. However, SVCI should be carefully performed because of potential complications such as phrenic nerve paralysis, SVC stenosis, and sinus node injury There are two major different approaches to treat SVC focus in the ablation of AF. The conventional approach is to perform SVCI only if AF from the SVC origin is actually recognized using pacing maneuvers and/or isoproterenol infusions. Another approach is the empiric empiricprophylactic SVCI in addition to PV isolation in all cases. The rate of AF freedom one year after initial AF ablation by empiric SVCI was almost same as the conventional method (85-90% AF freedom). Additionally, the conventional method has also a good result even 5 years after ablation (,73.3% AF freedom). Because of the excellent result in the conventional approach and possible complications after the SVCI, the empiric SVCI + PVI in all AF cases is still controversial. Patients with a long SVC myocardial sleeve are possible candidates for empiric SVCI in addition to PVI.
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Higuchi et al. (2014) studied this question.
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