Why the study?
To present current knowledge on adipose tissue inflammation associated with obesity and its relationship with pathologies like insulin resistance and mitochondrial dysfunction.
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Design
Review
Obesity-linked inflammation may refine CV risk assessment; leaves open targeted interventions pending prospective trials.
Obesity is one of the main health problems worldwide. It is a disease that is associated with excessive food consumption, although it is also associated with a process of chronic inflammation and with a group of disorders known as metabolic syndrome. Some of the most distinctive characteristics of obesity are that the individual's adipocytes are hypertrophied, have an irregular adipokine secretion profile, have increased recruitment of inflammatory cells, and altered metabolic homeostasis; which eventually results in the development of various important pathologies or conditions, such as insulin resistance and mitochondrial dysfunction. This review aims to present the current knowledge on inflammation of adipose tissue associated with obesity.
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García-Ortega et al. (2023) studied this question.
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