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This study aims to characterize the clinical features and outcomes of severe iatrogenic botulism cases requiring mechanical ventilation.

Iatrogenic botulism induced by cosmetic injection requiring mechanical ventilation: clinical characteristics and outcomes

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This study aims to characterize the clinical features and outcomes of severe iatrogenic botulism cases requiring mechanical ventilation.
Retrospective analysis of ventilated patients with severe iatrogenic botulism from April 2024 to September 2025.
Data on clinical characteristics, treatment, and three-month outcomes were collected and analyzed.
Fifteen patients, primarily females with a mean age of 36.40, were included.
All patients presented with ptosis, dysarthria, dysphagia, limb weakness, and abdominal distension.
Average mechanical ventilation duration was 329.93 hours; 46.67% underwent tracheotomy.
At three-month follow-up, one patient reported residual facial paresis and dysphagia.

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Retrospective analysis shows severe iatrogenic botulism requiring ventilation in 15 cases, highlighting risks with unlicensed products.

Yang et al. (2026) studied this question.

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