Factors associated with early hematoma expansion in intracerebral hemorrhage and the value of non-contrast computed tomography imaging features combined with clinical data for early identification
Randomized trial evaluates NCCT features and clinical data for early hematoma expansion identification in ICH, suggesting practical risk stratification methods.
Key Points
This study aims to identify factors associated with early hematoma expansion in patients with intracerebral hemorrhage and assess the effectiveness of non-contrast CT imaging features combined with clinical data.
Analyzed 571 patients with spontaneous supratentorial intracerebral hemorrhage admitted from January 2022 to December 2025.
Evaluated five non-contrast CT signs related to hematoma expansion and established a scoring system based on significant signs.
Used univariate and multivariate logistic regression to identify independent factors and created a combined prediction model.
Four CT signs (black hole, swirl, blend, satellite) were significantly linked to hematoma expansion, forming a comprehensive imaging score.
Independent risk factors included irregular hematoma morphology, time to initial CT, male sex, and baseline CT attenuation.
The prediction model showed reliable performance through calibration and decision curve analysis.