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September 10, 2025Journal of Stroke and Cerebrovascular DiseasesOpen Access

Predicting Early Hematoma Enlargement in Spontaneous Intracerebral Hemorrhage: Hypocalcemia, Hyperglycemia, and CT Signs

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Authors

XTXiaoxue TanYZYuzhao ZhuFLFei Liu

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Overview

Retrospective analysis identifies hypocalcemia and hyperglycemia as key risk factors for hematoma enlargement, suggesting effective predictive strategies.

Key Points

  • Early hematoma enlargement strongly predicts higher mortality and disability outcomes in spontaneous intracerebral hemorrhage.
  • Patients with hematoma enlargement exhibited significantly lower calcium levels at 1.92 mmol/L compared to 2.41 mmol/L in non-HE patients.
  • Multivariate logistic regression analysis identified hypocalcemia, hyperglycemia, and specific CT signs as independent risk factors for hematoma enlargement.
  • The optimal predictive model for hematoma enlargement achieved an area under the curve of 0.959, indicating high sensitivity and specificity.

Cite This Study

Tan et al. (2025) studied this question.

synapsesocial.com/papers/68c1ce6754b1d3bfb60f54c6https://doi.org/10.1016/j.jstrokecerebrovasdis.2025.108433
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