August 7, 2026npj Cardiovascular HealthOpen Access
Optical coherence tomography in the identification and risk stratification of vulnerable coronary plaques
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Discussion
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Implication
Randomized trial reveals risk stratification of vulnerable coronary plaques in patients with atherosclerosis, suggesting improved diagnostic capabilities.
Key Points
- To assess the role of optical coherence tomography (OCT) in identifying vulnerable coronary plaques and their associated risks.
- Utilized optical coherence tomography (OCT) for in vivo assessment of coronary plaques.
- Evaluated plaque features linked to cardiovascular events in patients with stable and acute coronary syndromes.
- Explored the impact of advances in automation and AI for clinical applications.
- Identified OCT-defined high-risk morphology associated with plaque progression and adverse events.
- Demonstrated the additional information OCT provides, especially in diabetes and multivessel disease.
- Findings are risk markers and do not serve as standalone treatment recommendations.
Cite This Study
Theofilis et al. (2026) studied this question.