QASMTrans: An End-to-End QASM Compilation Framework with Pulse Generation for Near-Term Quantum Devices

QASMTrans is a lightweight, high-performance, C++-based quantum compiler that bridges abstract quantum algorithms to device-level control and is designed for just-in-time (JIT) deployment on QPU testbeds with tightly integrated FPGAs or CPUs. We focus on achieving fast transpilation times on circuits of interest, we find more than 10× faster compilation than Qiskit in some circuits with similar circuit quality, enabling transpilation of large, high-depth circuits in seconds. Unlike existing tools, QASMTrans offers end-to-end device-pulse compilation and direct quantum control integration with QICK, closing the gap between logical circuits and hardware control enabling closed-loop optimization. QASMTrans supports latency-aware Application-tailored Gate Sets (AGS) at the pulse level, identifying high-impact gate sequences on the circuit critical path and synthesizing optimized pulse schedules using pre-defined robust circuit ansatz. Validated through integrated QuTiP pulse-level simulation, this is found to significantly reduce execution latency and can improve final-state fidelity by up to 12% in some tested circuits. QASMTrans further implements device-aware, noise-adaptive transpilation that uses device calibration data for circuit placement on high-quality qubits and can focus on the circuit critical path to reduce transpilation-pass time while maintaining comparable fidelity. Additionally, it introduces circuit space sharing via calibration-aware device partitioning, enabling concurrent execution of multiple circuits or shots on a single QPU. Moreover, QASMTrans is entirely self-contained and has no external library dependencies, making it easy for practical deployment. By combining fast compilation, pulse-level control, and noise-aware optimization, QASMTrans enables real-time adaptive algorithms such as ADAPT-VQE and ADAPT-QAOA. Source code: http://github.com/pnnl/qasmtrans