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August 7, 2026BiomedicinesOpen Access

Profile of People Living with HIV Switching Prior Antiretroviral Treatment to a Doravirine-Based Regimen in the Real-World Clinical Setting in Greece: The Retrospective DORAVITO Study

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Authors

APAntonios PapadopoulosMAMyrto AstritiVPVasileios Papastamopoulos

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Overview

Retrospective chart review reveals patterns of switching to doravirine treatment in people living with HIV in Greece, indicating a trend towards regimen simplification and toxicity prevention.

Key Points

  • The aim is to explore characteristics of people living with HIV switching to doravirine-based therapy and the reasons behind this treatment choice.
  • Retrospective chart review of 110 adults living with HIV switched to doravirine-based regimens across 6 public hospitals in Greece.
  • Analysis of patient characteristics, switching patterns, and reasons for regimen change.
  • Data collection from 12 July 2023 to 31 October 2023.
  • 90.9% of participants were males with a mean age of 49.3 years.
  • 42.7% switched due to regimen simplification and 26.4% due to tolerability issues.
  • 60.9% of patients were proactively switched, with most prescribed DOR plus nucleoside reverse transcriptase inhibitors.

Cite This Study

Papadopoulos et al. (2026) studied this question.

synapsesocial.com/papers/6a758c4f847ab6d26c020586https://doi.org/10.3390/biomedicines14081761
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