Antibiotic application after double-tube VSD for patients with complex wound

Objective To explore the clinical effect of sdouble-tube VSD for patients with complex wound on different sites. Methods 100 patients with complex wound admitted to our hospital from October, 2017 to March, 2018 were selected as a study group, and 100 patients treated with traditional trauma treatment technology at our hospital during the same period were selected as a control group. And the plugging rate, antibiotic use time, and number of times of prescription change were compared between the two groups. Results The case numbers of good recovery of soft tissue defect or trauma, abdominal wound, hot burn, radioactive wound, and sternum wound granulation were 25, 12, 13, 15, and 15 in the study group, and were 12, 3, 4, 5 and 5in the control group (all P<0.05). The infection rate, plugging rate, and antibiotic use time were 5.0%, 5.0%, and (14.3±2.2) d in the study group, and were 15.0%, 14.0%, and (21.2±2.3) d (all P<0.05). The number of prescriptions was significantly lower in the study group than in the control group (P<0.05). Conclusion VSD in the treatment of patients with complex wounds can significantly reduce the time of using antibiotics. The technology should be within the prescribed negative pressure range; the negative pressure should be appropriately adjusted according to the actual situation of peoples and patients with physical differences. A too low or too high negative pressure is not conducive to wound recovery.