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December 2, 2020Journal of Food and Nutrition ResearchOpen Access

Chemical Composition, Antioxidant, Antimicrobial and Anticancer Activities of Licorice (Glycyrrhiza glabra L.) Root and Its Application in Functional Yoghurt

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Authors

GHGamal M. HamadAEAdel I. Abd ElazizSHSabria Hassan

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Overview

In vitro analysis demonstrates antioxidant, antimicrobial, and anticancer activities of licorice root extract, highlighting its viability as a functional food ingredient.

Key Points

  • To evaluate the nutritional profile, antimicrobial efficacy, antioxidant capacity, and anticancer potential of licorice root extract, as well as its sensory appeal in functional yoghurt.
  • Determined the chemical, sugar, fiber, and mineral composition of licorice root alongside its total phenolic content and specific compounds such as gallic acid.
  • Assessed antimicrobial activity against Gram-positive and Gram-negative bacteria, yeast, and fungi, and measured antioxidant IC50 values and apoptotic effects on MDA-MB-361 breast cancer cells.
  • Performed sensory evaluations on functional yoghurt fortified with licorice root aqueous extract.
  • Licorice root consisted primarily of sugars (40.47 g/100g) and fiber (38.41 g/100g), with calcium (112.2 mg/100g) representing the predominant mineral.
  • The aqueous extract exhibited broad-spectrum antimicrobial activity, strong antioxidant capacity (IC50: 29.92 ± 2.43 mg/g), and marked proapoptotic activity against MDA-MB-361 cells, with gallic acid as the most abundant phenolic component.
  • Sensory panel results showed that consumers preferred the licorice-fortified yoghurt over unfortified controls.

Cite This Study

Hamad et al. (2020) studied this question.

synapsesocial.com/papers/6a75939a756843cacbb2172fhttps://doi.org/10.12691/jfnr-8-12-3
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