Chronic Heart Failure Management: A Literature Review of Guideline-Directed Medical Therapy

Chronic heart failure (CHF) is a progressive condition with high morbidity and mortality rates worldwide. Guideline-Directed Medical Therapy (GDMT) offers evidence-based guidelines for treating CHF, including pharmacological therapies that have been shown to improve patient outcomes. Despite its benefits, GDMT implementation varies across regions due to factors such as patient non-adherence, healthcare provider gaps, and systemic challenges. This literature review summarizes the current understanding of GDMT, focusing on its components, clinical efficacy, implementation challenges, and strategies to enhance adherence. This literature was conducted using databases such as Google Scholar, PubMed, and ScienceDirect using keywords relevant to chronic heart failure and guideline-directed medical therapy. The review highlights the importance of collaborative efforts to bridge the gap between guideline recommendations and practices, especially in resource-constrained settings, in order to maximize care for CHF patients.