Why the study?
Does acute hyperglycaemia prolong QTc duration and dispersion in patients with Type 1 diabetes and healthy volunteers?
Population
35 males, all non-smokers without any diabetic complications.
Comparison
Induction of acute hyperglycaemia for 120 min vs Normoglycaemia (baseline)
Design
Other
Follow-up
120 min
Authors
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May warrant QTc monitoring during hyperglycaemic excursions in T1D; leaves open arrhythmic risk in larger prospective studies.
Does acute hyperglycaemia prolong QTc duration and dispersion in patients with Type 1 diabetes and healthy volunteers?
Acute hyperglycaemia prolongs ventricular repolarization (QTc interval) in both Type 1 diabetics and healthy individuals, potentially increasing the risk of cardiovascular events.
Gordin et al. (2008) studied this question.
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