Why the study?
Does octreotide improve daytime hypotension and prevent nocturnal hypertension in subjects with primary autonomic failure?
Does octreotide improve daytime hypotension and prevent nocturnal hypertension in subjects with primary autonomic failure?
In patients with primary autonomic failure, octreotide effectively reduces daytime postural, postprandial, and exertion-induced hypotension without exacerbating nocturnal hypertension.
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Supports octreotide for daytime hypotension in autonomic failure without nocturnal worsening; confirms RCT benefit on 24-hour BP profiles.
Pavitt et al. (1995) studied this question.
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