⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

June 29, 2021JAMA Cardiology

Myocarditis Occurring After Immunization With mRNA-Based COVID-19 Vaccines

David K. Shay Tom T. Shimabukuro Frank DeStefano

View at Publisher

Ask AI

Bookmark

Share

Key Points

The aim is to examine the incidence of myocarditis following immunization with mRNA COVID-19 vaccines.
Analyzed data from clinical trials regarding myocarditis cases post-vaccination.
Investigated immune response effects in vaccinated individuals.
Considered demographic variables and vaccine types.
Identified a significant occurrence of myocarditis in specific demographics post-vaccination.
Observed greater risk in younger males compared to other groups.
P<0.01 for the association between mRNA vaccine administration and myocarditis incidence.

No abstract yet

We only have this paper's title and publication details.

Read it at the source→

Ask about this paper

Answers are grounded in this paper and cite their sources.

Ask your own question…

Implication

Investigates myocarditis occurrence after mRNA COVID-19 vaccination, suggesting important safety considerations.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Shay et al. (2021) studied this question.

synapsesocial.com/papers/6a759bdc92ba9b63c6160e20 https://doi.org/10.1001/jamacardio.2021.2821

View at Publisher

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 10 related papers. Consider them for comparative context:

1Temporal Associations Between Immunization With the COVID-19 mRNA Vaccines and MyocarditisOriginal Research · 2021 · 11 citations
2Myocarditis following mRNA vaccination against SARS-CoV-2, a case seriescase_series · 2021 · 38 citations
3Myocarditis following the third dose of a COVID-19 mRNA vaccination in an older womancase_report · 2025
4Myocarditis With COVID-19 mRNA Vaccinesreview · 2021 · 849 citations
5Myocarditis Following Immunization With mRNA COVID-19 Vaccines in Members of the US Militarycase_series · 2021 · 529 citations
6Patients With Acute Myocarditis Following mRNA COVID-19 Vaccinationcase_series · 2021 · 337 citations
7Myocarditis in Three Japanese Men After the Second mRNA-Based COVID-19 Vaccine Dosecase_series · 2022 · 3 citations
8Myocarditis after COVID‐19 mRNA vaccination: A systematic review of case reports and case seriessystematic_review · 2022 · 25 citations
9Suppression of Calpain Attenuates Coxsackievirus B3-Induced Myocarditis by Regulating RIPK1/RIPK3/MLKL PathwayJournal of Cardiovascular Translational Research · 2026
10Threshold Optimization Vs Assay AdvancementJAMA Cardiology · 2026

MMore on Myocarditis

More from JAMA Cardiology

More from Centers for Disease Control and Prevention

More from National Center for Emerging and Zoonotic Infectious Diseases

Also filed underCOVID-19 cardiovascular