Why the study?
What is the prevalence of mitral valve prolapse and other cardiac abnormalities in patients aged 60 years or less with transient cerebral ischemic attacks?
What is the prevalence of mitral valve prolapse and other cardiac abnormalities in patients aged 60 years or less with transient cerebral ischemic attacks?
A significant proportion (42%) of young patients with transient cerebral ischemic attacks have underlying cardiac abnormalities, supporting the routine use of echocardiography in this population.
Cardiac abnormalities appear common in young patients with reversible cerebral ischemia; this Level 4 finding leaves open the role of routine echocardiography.
The establishment of a possible association between ischemic cerebral attacks and prolapsing mitral valve has been studied in 45 consecutive patients aged 60 years or less with transient cerebral ischemic attacks and reversible ischemic neurological deficits. The study comprised cardiac history, auscultation, electrocardiography and echocardiography. We found only one patient (2%) with mitral valve prolapse but 19 patients (42%) with cardiac abnormalities. Two of the patients with cardiac abnormalities had a flail posterior mitral leaflet, one had ventricular septal defect and one had sclerotic aortic valves. We conclude that all patients with transient cerebral ischemic attacks should be subjected to heart examination, if possible including echocardiography.
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Scheibel et al. (1985) studied this question.
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