Key result
Obesity was independently associated with successful spinal anesthesia outcomes (OR 2.86) and a significantly lower incidence of anesthesia failure compared to non-obese patients.
Why the study?
Does obesity (BMI ≥ 30 kg/m2) affect the success and duration of spinal anesthesia with hyperbaric bupivacaine in patients undergoing total knee replacement arthroplasty?
Population
209 patients undergoing elective total knee replacement arthroplasty under spinal anesthesia. Excluded…
Comparison
Obese status in patients receiving spinal… vs Non-obese status in patients receiving the same…
Design
Cohort, Anesthesiologists and outcome assessors were aware of the group…
Follow-up
Until first self-void and first report of postoperative pain
Authors
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May guide anesthesia planning in obese TKA patients; leaves open causal effects and needs RCT confirmation.
Observational (n=209)
Single-blind
No
Does obesity (BMI ≥ 30 kg/m2) affect the success and duration of spinal anesthesia with hyperbaric bupivacaine in patients undergoing total knee replacement arthroplasty?
Odds Ratio: 2.86 (95% CI 1.25–6.52)
Absolute Event Rate: 85.3% vs 69.5%
p-value: p=0.013
Obesity is independently associated with a higher success rate and prolonged duration of spinal anesthesia using hyperbaric bupivacaine.
Kim et al. (2015) conducted an observational in Elective total knee replacement arthroplasty (TKRA) under spinal anesthesia (n=209). Obesity (BMI ≥ 30 kg/m2) vs. Non-obese (BMI < 30 kg/m2) was evaluated on Successful spinal anesthesia (bilateral T12 sensory block within 15 minutes and ≥T12 level at the end of surgery) (OR 2.86, 95% CI 1.25-6.52, p=0.013). Obesity was independently associated with successful spinal anesthesia outcomes (OR 2.86) and a significantly lower incidence of anesthesia failure compared to non-obese patients.
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