Answers are grounded in this paper and cite their sources.
Lipoteichoic acid (LTA) and peptidoglycan (PEG) from Staphylococcus aureus induced interleukin-5 (IL-5) production in human peripheral blood mononuclear cells (PBMC) from patients with atopic dermatitis (AD) but not in PBMC from healthy donors. The production of IL-5 induced by LTA or PEG was correlated with the expression of IL-5 mRNA in PBMC. Furthermore, the level of IL-5 production induced by treatment with both LTA and PEG from S. aureus was higher than that induced by the addition of each alone. These results suggest that LTA and PEG have an additive effect on IL-5 production in PBMC from AD patients and may explain the role of colonization with nontoxin-producing strains of S. aureus in these patients.
No takes yet. Share an insight, caveat, or question.
Matsui et al. (2000) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: