Experimental and theoretical study of the Raman spectra of ganoderic acid T

Ganoderic acid T (GAT) has many pharmacological functions such as antitumor and antimycobacterial activity. However, to the best of our knowledge, no commercial high-purity GAT is available and the experimental and theoretical study of Raman spectrum of GAT has never been reported up to date. Therefore, in this work, GAT was extracted and purified from the mycelia of G. lucidum by ourselves, and its Raman spectrum was measured and analyzed based on density functional theory (DFT) calculation at B3LYP/6-311+G(d, p) level. The research on the molecular structural and spectral properties may lead to deeper insights into the functions and better applications of GAT.