Key result
A low-intensity initiation of chemotherapy followed by a standard full-dose R-CHOP regimen achieved complete remission of primary cardiac lymphoma without cardiovascular complications.
Why the study?
Does a low intensity initiation of chemotherapy prevent cardiovascular complications in patients with primary cardiac lymphoma?
Population
A patient with primary cardiac lymphoma (PCL)
Design
Case_report
Authors
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May support monitored low-intensity chemotherapy start in primary cardiac lymphoma; hypothesis-generating case report requiring prospective validation.
Case Report (n=1)
Does a low intensity initiation of chemotherapy prevent cardiovascular complications in patients with primary cardiac lymphoma?
A 'low and slow' initiation of chemotherapy with CICU monitoring may safely achieve remission in primary cardiac lymphoma while mitigating the risk of catastrophic cardiovascular complications from rapid tumor destruction.
Shah et al. (2014) conducted a case report in Primary cardiac lymphoma (n=1). Low and slow chemotherapy (rituximab, prednisone, R-CHOP) was evaluated on Complete remission and resolution of intracardiac lymphoma. A low-intensity initiation of chemotherapy followed by a standard full-dose R-CHOP regimen achieved complete remission of primary cardiac lymphoma without cardiovascular complications.
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