Key result
Chronic lymphocytic leukemia was identified as a novel potential cause of aortic thrombosis in a dog presenting with exercise-induced lameness.
Why the study?
Although various neoplasms are recognized causes of aortic thrombosis, chronic lymphocytic leukemia had not yet been considered.
Case Report (n=1)
Highlights the importance of considering chronic lymphocytic leukemia as a possible cause of aortic thrombosis in dogs.
Answers are grounded in this paper and cite their sources.
May warrant CLL screening in dogs with aortic thrombosis; hypothesis-generating and requires prospective validation before adoption.
The aim of this report was to describe a case of aortic thrombosis (AT) secondary to chronic lymphocytic leukemia (CLL). Although, different types of neoplasms are described as possible causes of aortic thrombosis, CLL was not yet considered. The dog showed signs of lameness that worsened with exercise. The diagnosis of AT was made by ultrasound examination. The diagnosis of CLL was made by necropsy, which showed the presence of small lymphocytes with the appearance of mature lymphocytes in the bone marrow, spleen, liver and kidneys. The importance of including CLL in the possible causes of AT in dogs, in addition to the suspicion of AT in cases of neuromuscular disease, was highlighted.
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Ripplinger et al. (2020) conducted a case report in Aortic thrombosis and chronic lymphocytic leukemia (n=1). Chronic lymphocytic leukemia was evaluated on Diagnosis of aortic thrombosis and chronic lymphocytic leukemia. Chronic lymphocytic leukemia was identified as a novel potential cause of aortic thrombosis in a dog presenting with exercise-induced lameness.
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