Key result
A 12-week comprehensive lifestyle medicine program significantly improved peak VO2 max by 1.94 mL/kg/min and reduced supine systolic blood pressure by 9.70 mm Hg in poststroke veterans.
Why the study?
Comprehensive lifestyle medicine programs show efficacy in cerebrovascular disease, and the VA health care system has a large poststroke population with significant rehabilitation resources.
Does a 12-week comprehensive lifestyle medicine program improve fitness, function, and blood pressure in poststroke veterans?
Observational (n=14)
No
Does a 12-week comprehensive lifestyle medicine program improve fitness, function, and blood pressure in poststroke veterans?
Mean Difference: 1.94 (95% CI 0.96–2.9)
Absolute Event Rate: 20.2% vs 18.26%
p-value: p=0.001
A 12-week lifestyle medicine program significantly improved cardiovascular fitness, physical function, and blood pressure in poststroke veterans.
Supports lifestyle interventions for poststroke veterans; hypothesis-generating and requires randomized trials before practice change.
Comprehensive lifestyle medicine programs have begun to show efficacy in patients with cerebrovascular disease. The Veterans Affairs (VA) health care system has a large poststroke population and VA rehabilitation departments have significant expertise and resources for promoting healthy lifestyles. A 12-week clinical lifestyle medicine program was therefore implemented for poststroke patients, along with an optional observational study evaluating cardiovascular fitness, function, body composition, vitals, and quality of life before and after the program. Seventeen of 18 clinical patients elected to participate in the study, and 3 later withdrew. The 14 participants improved VO 2 max by 1.94 mL O 2 /min/kg ( P = .001, 95% CI 0.96-2.90). Significant improvements were seen in estimated metabolic equivalents, exercise duration, 6-minute walk test, 30-second sit to stand, grip strength, and balance. Among patients who were hypertensive at baseline, mean decrease in supine systolic blood pressure (SBP) was −9.70 mm Hg (n = 10, P = .005, 95% CI −15.7 to −3.7) and standing SBP was −11.09 mm Hg (n = 11, P = .009, 95% CI −18.7 to −3.48). There were no significant improvements in laboratory measures or body composition. Participant satisfaction was high. These findings corroborate recent literature suggesting that lifestyle programs improve stroke recovery and reduce recurrence risk.
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Krauss et al. (2021) conducted an observational in Poststroke (TIA or mild-moderate stroke) (n=14). Comprehensive lifestyle medicine program vs. Baseline (pre-intervention) was evaluated on Peak VO2 max (mL/kg/min) (MD 1.94, 95% CI 0.96-2.90, p=0.001). A 12-week comprehensive lifestyle medicine program significantly improved peak VO2 max by 1.94 mL/kg/min and reduced supine systolic blood pressure by 9.70 mm Hg in poststroke veterans.
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