What question did this study set out to answer?

Determine whether AUX/IAA family genes directly mediate downstream auxin responses in Arabidopsis through molecular analysis of the AXR3 gene.

February 27, 1998Science

Changes in Auxin Response from Mutations in an AUX/IAA Gene

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Authors

DRDean RouseAustralian National University PMPamela MackayMcGill University PSPetra StirnbergUniversity of York

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Implication

Genetic analysis demonstrates altered hormone responses from AXR3 mutations in Arabidopsis, indicating that AUX/IAA family members control downstream auxin signaling.

Key Points

Determine whether AUX/IAA family genes directly mediate downstream auxin responses in Arabidopsis through molecular analysis of the AXR3 gene.
Characterized Arabidopsis plants carrying gain-of-function and loss-of-function mutations in the AXR3 gene.
Evaluated phenotypic auxin responses and determined sequence homology between AXR3 and members of the AUX/IAA gene family.
Identified AXR3 as a member of the AUX/IAA gene family, establishing that these genes directly mediate auxin signaling.
Demonstrated that gain-of-function and loss-of-function mutations alter conserved domains shared among AUX/IAA proteins, resulting in diverse phenotypic changes in auxin responsiveness.

Cite This Study

Rouse et al. (1998) studied this question.

synapsesocial.com/papers/6a75b5c4d17bc701ee161a60 https://doi.org/10.1126/science.279.5355.1371

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Implication

Genetic analysis demonstrates altered hormone responses from AXR3 mutations in Arabidopsis, indicating that AUX/IAA family members control downstream auxin signaling.

Changes in Auxin Response from Mutations in an AUX/IAA Gene

Discussion

Member takes

Implication

Key Points

Cite This Study

Changes in Auxin Response from Mutations in an AUX/IAA Gene

Discussion

Member takes

Implication

Key Points

Cite This Study

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