Key result
Early hyperlactatemia after cardiac surgery was associated with significantly increased hospital mortality (3.8% vs 0%) and morbidity, whereas late hyperlactatemia had a benign course.
Why the study?
Postoperative hyperlactatemia is linked to worse outcomes in cardiac surgery, but data on the effect of the timing of hyperlactatemia on clinical outcomes remain scarce.
Does early hyperlactatemia compared to late hyperlactatemia predict worse clinical outcomes in adult patients undergoing cardiac surgery?
Observational (n=305)
No
Does early hyperlactatemia compared to late hyperlactatemia predict worse clinical outcomes in adult patients undergoing cardiac surgery?
Absolute Event Rate: 3.8% vs 0%
p-value: p=0.009
Early hyperlactatemia after cardiac surgery is associated with increased morbidity and mortality, whereas late hyperlactatemia is common and generally follows a benign, self-limiting course.
No takes yet. Share an insight, caveat, or question.
Early hyperlactatemia may identify higher-risk cardiac surgery patients; hypothesis-generating and requires prospective validation before practice change.
Khaled D. Algarni (2020) conducted an observational in Patients undergoing open cardiac surgery (n=305). Early hyperlactatemia (lactate > 3 mmol/L in the first hour after surgery) vs. No early hyperlactatemia was evaluated on Hospital mortality (p=0.009). Early hyperlactatemia after cardiac surgery was associated with significantly increased hospital mortality (3.8% vs 0%) and morbidity, whereas late hyperlactatemia had a benign course.
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