Key result
Modified rotational atherectomy plus drug-eluting stents was associated with a 14.5% 2-year MACE rate, compared to 30.5% for drug-coated balloons and 26.0% for plain balloons.
Why the study?
Previous studies on rotational atherectomy outcomes were limited by small sample sizes and low-risk populations.
Does a modified rotational atherectomy technique improve outcomes in aged, high-risk patients undergoing PCI for complex calcified lesions?
Cohort (n=1,169)
Does a modified rotational atherectomy technique improve outcomes in aged, high-risk patients undergoing PCI for complex calcified lesions?
Modified rotational atherectomy is a safe and effective technique for complex calcified lesions in high-risk patients, with RA followed by drug-eluting stent implantation showing the lowest MACE rates at 2 years.
No takes yet. Share an insight, caveat, or question.
Should not yet change practice; leaves open whether modified rotational atherectomy improves outcomes over balloons.
Dong et al. (2020) conducted a cohort in Coronary artery disease with calcified lesions or in-stent restenosis (n=1,169). Modified rotational atherectomy (RA) + drug-eluting-stent (DES) vs. RA + drug-coated balloon or RA + plain old balloon angioplasty was evaluated on Major adverse cardiac events (MACE) at 2 years. Modified rotational atherectomy plus drug-eluting stents was associated with a 14.5% 2-year MACE rate, compared to 30.5% for drug-coated balloons and 26.0% for plain balloons.
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