Why the study?
Do standing and isometric exercise cause abnormal plasma epinephrine and norepinephrine responses in insulin-dependent diabetic subjects compared to controls?
Population
10 healthy, insulin-dependent diabetic subjects and 10 matched control adults (n=20)
Comparison
Standing and isometric exercise vs Matched control adults undergoing the same…
Design
Case-control
Follow-up
Acute (approx. 60 minutes of protocol)
Authors
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May indicate early sympathoadrenal changes in diabetes; leaves open prognostic value and need for prospective validation.
Do standing and isometric exercise cause abnormal plasma epinephrine and norepinephrine responses in insulin-dependent diabetic subjects compared to controls?
Insulin-dependent diabetic patients exhibit exaggerated epinephrine and heart rate responses to standing and isometric exercise, suggesting an early sympathoadrenal defect.
Gustafson et al. (1981) studied this question.