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November 1, 1973Antimicrobial Agents and ChemotherapyOpen Access

Isolation and Identification of Minor Components of Commercial Kanamycin

P. Claes H. Vanderhaeghe Frans Compernolle

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Abstract

A fraction enriched in the minor components of the kanamycin complex was prepared from a commercial sample. The enriched fraction was subjected to Amberlite CG-50 and Dowex 1-X2 column chromatography. Two minor components were isolated in addition to the known A, B, and C components. These congeners were identified as paromamine and 6-o-(3-amino-3-deoxy-alpha-d-glucopyranosyl)- deoxystreptamine. The identification was based on degradation and mass spectral studies.

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Claes et al. (1973) studied this question.

synapsesocial.com/papers/6a75c220fbccc8f4fd161feb https://doi.org/10.1128/aac.4.5.560

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