What question did this study set out to answer?

To assess and compare echocardiographic indices in female dogs anesthetized with dexmedetomidine-ketamine versus midazolam-ketamine during elective ovariohysterectomy.

January 1, 2024Open Access

Echocardiographic indices probe during dexmedetomidine/midazolam - ketamine anesthesia in dogs undergoing ovariohysterectomy.

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Authors

APAnju PooniaGuru Angad Dev Veterinary and Animal Sciences University DTDeepak Kumar TiwariNIMS University SSSandeep SaharanLala Lajpat Rai University of Veterinary and Animal Sciences

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Implication

Randomized trial reveals midazolam maintains superior cardiac stability over dexmedetomidine during ketamine anesthesia in dogs, suggesting safer hemodynamics during canine surgery.

Key Points

To assess and compare echocardiographic indices in female dogs anesthetized with dexmedetomidine-ketamine versus midazolam-ketamine during elective ovariohysterectomy.
Randomized trial of 28 female dogs undergoing elective ovariohysterectomy, assigned to receive either dexmedetomidine (GDEX, n=14) or midazolam (GMID, n=14) alongside ketamine.
Evaluated physiological parameters and echocardiographic indices across four intervals: baseline (T0), 10 minutes post-sedation (T1), post-induction (T2), and at surgery completion (T3).
Heart rate was significantly higher at T1, T2, and T3 in the GMID group compared to GDEX, whereas rectal temperature was significantly lower at T3 in GMID.
Both groups exhibited a significant reduction in stroke volume, cardiac output, ejection fraction, and fractional shortening at T1, followed by a significant increase at T2 and subsequent decline at T3.
GMID produced minimal alterations in systolic function compared to GDEX, demonstrating superior cardiovascular stability overall.

Cite This Study

Poonia et al. (2024) studied this question.

synapsesocial.com/papers/6a75c59e756843cacbb22be4 https://doi.org/10.30466/vrf.2024.2019897.4130

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Implication

Randomized trial reveals midazolam maintains superior cardiac stability over dexmedetomidine during ketamine anesthesia in dogs, suggesting safer hemodynamics during canine surgery.

Echocardiographic indices probe during dexmedetomidine/midazolam - ketamine anesthesia in dogs undergoing ovariohysterectomy.

Discussion

Member takes

Implication

Key Points

Cite This Study

Echocardiographic indices probe during dexmedetomidine/midazolam - ketamine anesthesia in dogs undergoing ovariohysterectomy.

Discussion

Member takes

Implication

Key Points

Cite This Study

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