September 1, 1991Journal of the American Chemical Society
Atomic structure of the rapamycin human immunophilin FKBP-12 complex
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Implication
This research reveals the atomic structure of the rapamycin FKBP-12 complex, suggesting insights for future applications.
Key Points
- The goal is to determine the atomic structure of the rapamycin complex with FKBP-12.
- Performed X-ray crystallography to elucidate the atomic structure of the rapamycin-FKBP-12 complex.
- The study presents a detailed atomic model of rapamycin binding to FKBP-12, providing insights into the structural basis for their interaction.
Cite This Study
Duyne et al. (1991) studied this question.