Why the study?
Does electromyographic study reveal defects of neuromuscular transmission in patients with prior poliomyelitis?
Population
Patients examined long after subsidence of acute poliomyelitis infection
Design
Cross-sectional
Authors
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Suggests junctional defects contribute to post-polio weakness; leaves open therapeutic implications pending prospective confirmation.
Does electromyographic study reveal defects of neuromuscular transmission in patients with prior poliomyelitis?
This study provides evidence that poliomyelitis involves defects at the neuromuscular junction, not just destruction of somatic motor neurons.
Robert Hodes (1948) studied this question.
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