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August 1, 2002Arthritis & Rheumatism

Sites of collagenase cleavage and denaturation of type II collagen in aging and osteoarthritic articular cartilage and their relationship to the distribution of matrix metalloproteinase 1 and matrix metalloproteinase 13

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Authors

William Ka Kei Wu
William Ka Kei WuQuantitative BioSciencesRBR. Clark BillinghurstPortsmouth CollegeIPIsabelle PidouxMontreal Children's Hospital

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Wu et al. (2002) studied this question.

synapsesocial.com/papers/6a75dc4bfbccc8f4fd16285chttps://doi.org/10.1002/art.10428
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  1. 1Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the knee1986 · 6,850 citations
  2. 2Selective enhancement of collagenase-mediated cleavage of resident type II collagen in cultured osteoarthritic cartilage and arrest with a synthetic inhibitor that spares collagenase 1 (matrix metalloproteinase 1)2000 · 243 citations
  3. 3Type II collagen degradation in spontaneous osteoarthritis in C57BL/6 and BALB/c mice1999 · 80 citations