Key result
Peak CK-MB mass ≥25 μg/L after elective cardiac surgery was associated with increased all-cause mortality and readmission for acute coronary syndromes compared to <25 μg/L (30.0% vs 17.9%, p=0.022).
Why the study?
Does elevated CK-MB mass after elective cardiac surgery predict long-term adverse events in low-risk patients with stable angina?
Population
230 consecutive low-risk patients with stable angina undergoing elective cardiac surgery.
Comparison
Peak CK-MB mass values ≥25 microg/l after surgery. vs Peak CK-MB mass values <25 microg/l.
Design
Cohort
Follow-up
median 95 months
Authors
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May identify higher-risk patients for closer surveillance post-surgery; leaves open whether targeted interventions improve outcomes in low-risk cases.
Cohort (n=230)
Does elevated CK-MB mass after elective cardiac surgery predict long-term adverse events in low-risk patients with stable angina?
Absolute Event Rate: 30% vs 17.9%
p-value: p=0.022
Elevated CK-MB mass (≥5 times the reference) after elective cardiac surgery in low-risk patients is independently associated with reduced long-term event-free survival.
Vikenes et al. (2008) conducted a cohort in Stable angina (n=230). Peak CK-MB mass ≥25 μg/L vs. Peak CK-MB mass <25 μg/L was evaluated on All-cause mortality and readmission for acute coronary syndromes (p=0.022). Peak CK-MB mass ≥25 μg/L after elective cardiac surgery was associated with increased all-cause mortality and readmission for acute coronary syndromes compared to <25 μg/L (30.0% vs 17.9%, p=0.022).
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