Key result
Abdominal aorto-venocaval shunt (AVS) induced spontaneous electrical activity in one third of isolated rat pulmonary-vein preparations compared to scarcely any in sham-operated rats.
Why the study?
Does chronic volume overload induced by abdominal aorto-venocaval shunt increase automaticity in the pulmonary-vein myocardium of rats?
Population
Rats with abdominal aorto-venocaval shunt (AVS) as a model of chronic volume overload
Comparison
Abdominal aorto-venocaval shunt (AVS) vs Sham-operated rats
Design
Preclinical
Authors
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Should not yet change practice; leaves open pulmonary vein triggers in volume-overload models.
Does chronic volume overload induced by abdominal aorto-venocaval shunt increase automaticity in the pulmonary-vein myocardium of rats?
Chronic volume overload induced by an abdominal aorto-venocaval shunt manifests automaticity in the rat pulmonary-vein myocardium, providing insights into arrhythmogenesis.
Hamaguchi et al. (2015) studied chronic volume overload. abdominal aorto-venocaval shunt (AVS) vs. sham-operated rats was evaluated on Spontaneous electrical activity in isolated pulmonary-vein preparations. Abdominal aorto-venocaval shunt (AVS) induced spontaneous electrical activity in one third of isolated rat pulmonary-vein preparations compared to scarcely any in sham-operated rats.
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