Key result
A 58-year-old African-American female with recurrent chest pain was diagnosed with apical hypertrophic cardiomyopathy (Yamaguchi syndrome) via left ventriculography after non-conclusive stress tests.
Case Report (n=1)
This case highlights the rare occurrence of apical hypertrophic cardiomyopathy in an African-American patient and emphasizes the diagnostic utility of ventriculography when echocardiography and stress tests are non-conclusive.
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May prompt ventriculography in inconclusive apical HCM cases; leaves open ethnic prevalence questions.
Apical hypertrophic cardiomyopathy (ApHCM) is a rare variant of hypertrophic cardiomyopathy, characterized by a spade-like left ventricular cavity. A 58-year-old African-American female with past medical history of hypertension presented for evaluation of recurrent exertional chest tightness, palpitations and headache. Prior workup including multiple stress tests and angiogram was non-conclusive. Electrocardiogram (EKG) showed characteristic marked T-waves inversions in inferior leads and left ventriculography revealed left ventricle apical hypertrophy with spade like left ventricular cavity that was typical of Yamaguchi syndrome. This case highlights the rare incidence of the disease among African American as well as the challenging diagnostic and presentation features of the disease.
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Abugroun et al. (2017) conducted a case report in Apical Hypertrophic Cardiomyopathy (n=1). Diagnostic evaluation (EKG, Coronary angiography, Left ventriculography) was evaluated on Diagnosis of Apical Hypertrophic Cardiomyopathy (Yamaguchi syndrome). A 58-year-old African-American female with recurrent chest pain was diagnosed with apical hypertrophic cardiomyopathy (Yamaguchi syndrome) via left ventriculography after non-conclusive stress tests.
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