Population
Human blood platelets from 3 Glanzmann's thrombasthenia patients and normal donors
Design
Preclinical
Authors
Loading...
Thrombospondin may mediate platelet aggregation; leaves open targeted inhibition as a human therapeutic strategy.
The anti-thrombospondin monoclonal antibody P8 inhibits platelet aggregation, suggesting thrombospondin plays an active role in promoting aggregation and binds to a receptor distinct from the GPIIb-IIIa complex.
Boukerche et al. (1988) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: