Key result
A simulated stent in place of severe renal artery stenosis decreased flow resistance to levels comparable to a healthy artery, whereas the stenotic artery exhibited pressure gradients many orders of magnitude larger.
Computational fluid dynamics using turbulence modeling can non-invasively characterize hemodynamically significant renal artery stenosis and predict the hemodynamic effects of stenting.
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Highlights CFD potential for RAS hemodynamics; leaves open clinical translation and stenting decisions.
Kagadis et al. (2007) studied Severe renal artery stenosis (n=1). Simulated endovascular stent implantation vs. Simulated severe renal artery stenosis (pre-treatment) and simulated healthy artery was evaluated on Hemodynamic parameters including pressure gradients, flow resistance, and wall shear stress. A simulated stent in place of severe renal artery stenosis decreased flow resistance to levels comparable to a healthy artery, whereas the stenotic artery exhibited pressure gradients many orders of magnitude larger.
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