Key result
Surgical resection of primary cardiac masses was associated with a 10-year all-cause mortality of 14% in a cohort predominantly diagnosed with benign tumors.
Why the study?
Cardiac tumors represent a rare and heterogenous pathologic entity, prompting this study to investigate clinical presentation and long-term outcomes after surgical resection.
What are the long-term survival outcomes following surgical resection of benign and malignant cardiac masses?
Cohort (n=183)
No
What are the long-term survival outcomes following surgical resection of benign and malignant cardiac masses?
Surgical resection of primary cardiac tumors is highly effective, with a 10-year all-cause mortality of 14% in a cohort predominantly consisting of benign tumors.
May inform surgical planning for rare cardiac tumors; leaves open need for prospective trials to guide practice.
INTRODUCTION: Cardiac tumors represent a rare and heterogenous pathologic entity, with a cumulative incidence of up to 0.02%. This study aimed to investigate one of the largest patient cohorts published for clinical presentation and long-term outcomes after surgical resection. AREAS COVERED: Between 2009 and 2021, 183 consecutive patients underwent surgery for tumor excision in our center. Preoperative baseline characteristics, intraoperative data, and long-term survival were analyzed. The diagnosis was confirmed postoperatively by histology and Immunohistochemical investigations. Kaplan-Meier curves assessed survival, and the Cox proportional hazards model, was used to identify prognostic factors for overall survival. RESULTS: This series included 183 consecutive patients; most (n = 169, 92.3%) were diagnosed with benign cardiac masses. The mean age of patients was 60 ± 16 years, and 48% (n = 88) were females. The largest group of tumors was myxoma (n = 98; 54%). The most common malignant tumor type was sarcoma (n = 5; 2.7%). The mean hospital stay was 11 ± 6.5 days, and all-cause mortality after ten years was 14%. EXPERT OPINION: Surgery represents the gold standard in treating primary cardiac tumors; in benign tumors, it is highly effective and curative, whereas, in malignant tumors, it remains associated with more prolonged survival.
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Gaisendrees et al. (2022) conducted a cohort in Cardiac masses (n=183). Surgical resection was evaluated on All-cause mortality after ten years. Surgical resection of primary cardiac masses was associated with a 10-year all-cause mortality of 14% in a cohort predominantly diagnosed with benign tumors.
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