Why the study?
Does squatting enhance aortic wave reflection compared to standing in healthy young adults?
Does squatting enhance aortic wave reflection compared to standing in healthy young adults?
Squatting significantly enhances aortic wave reflection, providing a hemodynamic explanation for its known benefit in improving cyanotic spells in patients with tetralogy of Fallot.
May explain squatting benefit in tetralogy of Fallot; leaves open causal validation in patients.
BACKGROUND: Although "squatting" in patients with tetralogy of Fallot is famous, the hemodynamic mechanism of the phenomenon has not been fully elucidated. To clarify the mechanism of squatting, the change in aortic pulsatile property induced by squatting was investigated. METHODS: Twelve healthy young adults were enrolled in this study. The change in central pressure waveform induced by squatting was investigated using SphygmoCor (PWV Medical, Sydney, Australia). RESULTS: The augmentation index during squatting was higher than that during standing (mean +/- SEM, 6.3 +/- 1.1 v 25.0 +/- 1.1; P <.0001). The heart rate corrected augmentation index during squatting was also higher than that during standing (7.9 +/- 0.9 v 25.6 +/- 1.0; P <.0001). CONCLUSION: Squatting enhances the aortic wave reflection. It may cause a rise in aortic pressure and may improve cyanotic spells in patients with tetralogy of Fallot.
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Tomoaki Murakami (2002) studied this question.
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