F-18 FDG PET/CT can effectively identify rare complications such as IVC tumor invasion in patients with adrenocortical carcinoma.
May support FDG PET/CT for preoperative detection of IVC invasion in adrenocortical carcinoma; hypothesis-generating and leaves open prospective validation.
Tumor thrombus in the inferior vena cava (IVC) is a rare complication of adrenocortical carcinoma (ACC). We present a right ACC that was found on a routine health checkup and was confirmed by simultaneous measurements of late-afternoon serum cortisol and ACTH levels in a 65-year-old woman. Preoperative F-18 FDG PET/CT revealed intense F-18 FDG uptake in the right adrenal region with tumor invasion in the IVC. This PET result was also confirmed by subsequent abdominal MRI. The patient then had a right adrenalectomy with IVC thrombectomy. Pathologic analysis of the right adrenal tumor and the thrombus from the IVC was consistent with ACC.
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Cheng et al. (2007) studied this question.
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