September 4, 2015Journal of Hypertension

Blood pressure and early neurological deterioration in acute ischemic stroke

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Why the study?

Is high blood pressure and blood pressure variability associated with early neurological deterioration in patients with acute ischemic stroke?

Structured PICO

Is high blood pressure and blood pressure variability associated with early neurological deterioration in patients with acute ischemic stroke?

Population

1161 patients hospitalized for acute ischemic stroke within 24 h of onset

Intervention

High blood pressure (BP) and high BP variability (systolic and diastolic)

Outcome

Development of early neurological deterioration according to predefined criteria within the first 72 h of stroke onsethard clinical

Limitations

Increased BP variability may be a consequence of the underlying severity of the neurological damage and not necessarily the cause of it

Discussion

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Implication

High blood pressure and its variability in the acute phase of ischemic stroke are independently associated with early neurological deterioration, though causality remains uncertain.

Cite This Study

Kjeldsen et al. (2015) studied this question.

synapsesocial.com/papers/6a75fc5374b63c188eb20c30 https://doi.org/10.1097/hjh.0000000000000689

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Implication

High blood pressure and its variability in the acute phase of ischemic stroke are independently associated with early neurological deterioration, though causality remains uncertain.