A Triterpenoid Having Anticancer Activity Found in Stem Bark of Holoptelea integrifolia (Roxb.) Planch

Studies on the chemical constituents of the stem bark of Holoptelea integrifolia (Roxb.) Planch have led to the isolation of a triterpenoid, oleanolic acid (1), the structure of the compound was elucidated via advanced spectroscopic techniques including EI (+), IR, 1 H-NMR and 13 C-NMR. Oleanolic acid was isolated first time from the stem bark of H. integrifolia. Crude ethylacetate extract of the stem bark of H. integrifolia has been tested in vitro for its cytotoxicity by MTT assay. This paper is based on isolation and characterization of the chemical constituents.