Why the study?
It was unclear whether central hemodynamic parameters correlate with gut microbiota changes associated with exercise and dietary interventions in individuals with obesity.
Does a 6-week exercise and diet intervention improve central hemodynamics and alter gut microbiota in adolescents with obesity?
Population
24 adolescents with obesity (mean age 12.88 ± 0.41 years)
Comparison
Before vs after a 6-week exercise and dietary restriction program
Design
Pre-post interventional study
Follow-up
6 weeks
Authors
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May improve central hemodynamics in obese adolescents; hypothesis-generating for microbiota mediation, needs RCTs before practice change.
Does a 6-week exercise and diet intervention improve central hemodynamics and alter gut microbiota in adolescents with obesity?
A 6-week intensive exercise and diet intervention in obese adolescents significantly improved central hemodynamics and metabolic profiles, which correlated with beneficial shifts in gut microbiota composition.
Huang et al. (2020) studied this question.